Genome duplication in Leishmania major relies on persistent subtelomeric DNA replication

DNA replication is needed to duplicate a cell’s genome in S phase and segregate it during cell division. Previous work in Leishmania detected DNA replication initiation at just a single region in each chromosome, an organisation predicted to be insufficient for complete genome duplication within S p...

Descripción completa

Detalles Bibliográficos
Autores principales: Damasceno, Jeziel Dener, Marques, Catarina A, Beraldi, Dario, Crouch, Kathryn, Lapsley, Craig, Obonaga, Ricardo, Tosi, Luiz RO, McCulloch, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Genetics and Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7511235/
https://www.ncbi.nlm.nih.gov/pubmed/32897188
http://dx.doi.org/10.7554/eLife.58030

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7511235/
https://www.ncbi.nlm.nih.gov/pubmed/32897188
http://dx.doi.org/10.7554/eLife.58030

Ejemplares similares