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Genome duplication in Leishmania major relies on persistent subtelomeric DNA replication

DNA replication is needed to duplicate a cell’s genome in S phase and segregate it during cell division. Previous work in Leishmania detected DNA replication initiation at just a single region in each chromosome, an organisation predicted to be insufficient for complete genome duplication within S p...

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Detalles Bibliográficos
Autores principales:	Damasceno, Jeziel Dener, Marques, Catarina A, Beraldi, Dario, Crouch, Kathryn, Lapsley, Craig, Obonaga, Ricardo, Tosi, Luiz RO, McCulloch, Richard
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2020
Materias:	Genetics and Genomics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7511235/ https://www.ncbi.nlm.nih.gov/pubmed/32897188 http://dx.doi.org/10.7554/eLife.58030

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