Cargando…
Boundary sequences flanking the mouse tyrosinase locus ensure faithful pattern of gene expression
Control of gene expression is dictated by cell-type specific regulatory sequences that physically organize the structure of chromatin, including promoters, enhancers and insulators. While promoters and enhancers convey cell-type specific activating signals, insulators prevent the cross-talk of regul...
Autores principales: | Seruggia, Davide, Fernández, Almudena, Cantero, Marta, Fernández-Miñán, Ana, Gomez-Skarmeta, José Luis, Pelczar, Pawel, Montoliu, Lluis |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7511308/ https://www.ncbi.nlm.nih.gov/pubmed/32968154 http://dx.doi.org/10.1038/s41598-020-72543-0 |
Ejemplares similares
-
Functional validation of mouse tyrosinase non-coding regulatory DNA elements by CRISPR–Cas9-mediated mutagenesis
por: Seruggia, Davide, et al.
Publicado: (2015) -
A Slc38a8 Mouse Model of FHONDA Syndrome Faithfully Recapitulates the Visual Deficits of Albinism Without Pigmentation Defects
por: Guardia, Ana, et al.
Publicado: (2023) -
Binary recombinase systems for high-resolution conditional mutagenesis
por: Hermann, Mario, et al.
Publicado: (2014) -
An insulator embedded in the chicken α-globin locus regulates chromatin domain configuration and differential gene expression
por: Furlan-Magaril, Mayra, et al.
Publicado: (2011) -
A role for insulator elements in the regulation of gene expression response to hypoxia
por: Tiana, Maria, et al.
Publicado: (2012)