SUMO promotes longevity and maintains mitochondrial homeostasis during ageing in Caenorhabditis elegans

The insulin/IGF signalling pathway impacts lifespan across distant taxa, by controlling the activity of nodal transcription factors. In the nematode Caenorhabditis elegans, the transcription regulators DAF-16/FOXO and SKN-1/Nrf function to promote longevity under conditions of low insulin/IGF signal...

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Detalles Bibliográficos
Autores principales: Princz, Andrea, Pelisch, Federico, Tavernarakis, Nektarios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7511317/
https://www.ncbi.nlm.nih.gov/pubmed/32968203
http://dx.doi.org/10.1038/s41598-020-72637-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7511317/
https://www.ncbi.nlm.nih.gov/pubmed/32968203
http://dx.doi.org/10.1038/s41598-020-72637-9

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