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SUMO promotes longevity and maintains mitochondrial homeostasis during ageing in Caenorhabditis elegans
The insulin/IGF signalling pathway impacts lifespan across distant taxa, by controlling the activity of nodal transcription factors. In the nematode Caenorhabditis elegans, the transcription regulators DAF-16/FOXO and SKN-1/Nrf function to promote longevity under conditions of low insulin/IGF signal...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7511317/ https://www.ncbi.nlm.nih.gov/pubmed/32968203 http://dx.doi.org/10.1038/s41598-020-72637-9 |