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T-Plastin reinforces membrane protrusions to bridge matrix gaps during cell migration
Migrating cells move across diverse assemblies of extracellular matrix (ECM) that can be separated by micron-scale gaps. For membranes to protrude and reattach across a gap, actin filaments, which are relatively weak as single filaments, must polymerize outward from adhesion sites to push membranes...
Autores principales: | Garbett, Damien, Bisaria, Anjali, Yang, Changsong, McCarthy, Dannielle G., Hayer, Arnold, Moerner, W. E., Svitkina, Tatyana M., Meyer, Tobias |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7511357/ https://www.ncbi.nlm.nih.gov/pubmed/32968060 http://dx.doi.org/10.1038/s41467-020-18586-3 |
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