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T-Plastin reinforces membrane protrusions to bridge matrix gaps during cell migration

Migrating cells move across diverse assemblies of extracellular matrix (ECM) that can be separated by micron-scale gaps. For membranes to protrude and reattach across a gap, actin filaments, which are relatively weak as single filaments, must polymerize outward from adhesion sites to push membranes...

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Detalles Bibliográficos
Autores principales: Garbett, Damien, Bisaria, Anjali, Yang, Changsong, McCarthy, Dannielle G., Hayer, Arnold, Moerner, W. E., Svitkina, Tatyana M., Meyer, Tobias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7511357/
https://www.ncbi.nlm.nih.gov/pubmed/32968060
http://dx.doi.org/10.1038/s41467-020-18586-3

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