A multi-ethnic meta-analysis identifies novel genes, including ACSL5, associated with amyotrophic lateral sclerosis

Amyotrophic lateral sclerosis (ALS) is a devastating progressive motor neuron disease that affects people of all ethnicities. Approximately 90% of ALS cases are sporadic and thought to have multifactorial pathogenesis. To understand the genetics of sporadic ALS, we conducted a genome-wide associatio...

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Autores principales: Nakamura, Ryoichi, Misawa, Kazuharu, Tohnai, Genki, Nakatochi, Masahiro, Furuhashi, Sho, Atsuta, Naoki, Hayashi, Naoki, Yokoi, Daichi, Watanabe, Hazuki, Watanabe, Hirohisa, Katsuno, Masahisa, Izumi, Yuishin, Kanai, Kazuaki, Hattori, Nobutaka, Morita, Mitsuya, Taniguchi, Akira, Kano, Osamu, Oda, Masaya, Shibuya, Kazumoto, Kuwabara, Satoshi, Suzuki, Naoki, Aoki, Masashi, Ohta, Yasuyuki, Yamashita, Toru, Abe, Koji, Hashimoto, Rina, Aiba, Ikuko, Okamoto, Koichi, Mizoguchi, Kouichi, Hasegawa, Kazuko, Okada, Yohei, Ishihara, Tomohiko, Onodera, Osamu, Nakashima, Kenji, Kaji, Ryuji, Kamatani, Yoichiro, Ikegawa, Shiro, Momozawa, Yukihide, Kubo, Michiaki, Ishida, Noriko, Minegishi, Naoko, Nagasaki, Masao, Sobue, Gen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7511394/
https://www.ncbi.nlm.nih.gov/pubmed/32968195
http://dx.doi.org/10.1038/s42003-020-01251-2

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