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Automated AFM analysis of DNA bending reveals initial lesion sensing strategies of DNA glycosylases

Base excision repair is the dominant DNA repair pathway of chemical modifications such as deamination, oxidation, or alkylation of DNA bases, which endanger genome integrity due to their high mutagenic potential. Detection and excision of these base lesions is achieved by DNA glycosylases. To invest...

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Detalles Bibliográficos
Autores principales:	Bangalore, Disha M., Heil, Hannah S., Mehringer, Christian F., Hirsch, Lisa, Hemmen, Katherina, Heinze, Katrin G., Tessmer, Ingrid
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7511397/ https://www.ncbi.nlm.nih.gov/pubmed/32968112 http://dx.doi.org/10.1038/s41598-020-72102-7

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