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Difference in persistent tuberculosis bacteria between in vitro and sputum from patients: implications for translational predictions
This study aimed to investigate the number of persistent bacteria in sputum from tuberculosis patients compared to in vitro and to suggest a model-based approach for accounting for the potential difference. Sputum smear positive patients (n = 25) provided sputum samples prior to onset of chemotherap...
Autores principales: | Faraj, Alan, Clewe, Oskar, Svensson, Robin J., Mukamolova, Galina V., Barer, Michael R., Simonsson, Ulrika S. H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7511403/ https://www.ncbi.nlm.nih.gov/pubmed/32968142 http://dx.doi.org/10.1038/s41598-020-72472-y |
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