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Late i.v. steroid treatment for severe COVID‐19‐induced acute respiratory distress syndrome: a case report

BACKGROUND: The efficacy of steroid treatment for coronavirus disease (COVID‐19) is unknown. CASE PRESENTATION: A 67‐year‐old man was transported to our hospital due to impaired consciousness and respiratory failure. After admission, tracheal aspirate of the patient was harvested, and it tested posi...

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Autores principales: Kumakawa, Yasuaki, Hirano, Yohei, Sueyoshi, Koichiro, Ishihara, Tadashi, Kondo, Yutaka, Kawasaki, Takaaki, Takeuchi, Yuji, Nakamura, Yuki, Ishikawa, Kouhei, Watanabe, Yusuke, Saito, Wataru, Matsuda, Shigeru, Nakazawa, Takeshi, Sasaki, Shinichi, Okamoto, Ken, Tanaka, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7511560/
https://www.ncbi.nlm.nih.gov/pubmed/33005428
http://dx.doi.org/10.1002/ams2.569
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author Kumakawa, Yasuaki
Hirano, Yohei
Sueyoshi, Koichiro
Ishihara, Tadashi
Kondo, Yutaka
Kawasaki, Takaaki
Takeuchi, Yuji
Nakamura, Yuki
Ishikawa, Kouhei
Watanabe, Yusuke
Saito, Wataru
Matsuda, Shigeru
Nakazawa, Takeshi
Sasaki, Shinichi
Okamoto, Ken
Tanaka, Hiroshi
author_facet Kumakawa, Yasuaki
Hirano, Yohei
Sueyoshi, Koichiro
Ishihara, Tadashi
Kondo, Yutaka
Kawasaki, Takaaki
Takeuchi, Yuji
Nakamura, Yuki
Ishikawa, Kouhei
Watanabe, Yusuke
Saito, Wataru
Matsuda, Shigeru
Nakazawa, Takeshi
Sasaki, Shinichi
Okamoto, Ken
Tanaka, Hiroshi
author_sort Kumakawa, Yasuaki
collection PubMed
description BACKGROUND: The efficacy of steroid treatment for coronavirus disease (COVID‐19) is unknown. CASE PRESENTATION: A 67‐year‐old man was transported to our hospital due to impaired consciousness and respiratory failure. After admission, tracheal aspirate of the patient was harvested, and it tested positive for severe acute respiratory syndrome coronavirus 2 nucleic acid. He required veno‐venous extracorporeal membrane oxygenation to sustain his oxygenation. However, his respiratory failure did not improve for 20 days. On day 20 of admission, we started to use i.v. steroid therapy. On day 23, lung opacity on the chest X‐ray cleared and the patient’s oxygen saturation improved significantly. We successfully removed extracorporeal membrane oxygenation on day 27. CONCLUSION: Our case report encourages more future trials to evaluate the therapeutic use of i.v. steroid in severe COVID‐19‐induced acute respiratory distress syndrome.
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spelling pubmed-75115602020-09-30 Late i.v. steroid treatment for severe COVID‐19‐induced acute respiratory distress syndrome: a case report Kumakawa, Yasuaki Hirano, Yohei Sueyoshi, Koichiro Ishihara, Tadashi Kondo, Yutaka Kawasaki, Takaaki Takeuchi, Yuji Nakamura, Yuki Ishikawa, Kouhei Watanabe, Yusuke Saito, Wataru Matsuda, Shigeru Nakazawa, Takeshi Sasaki, Shinichi Okamoto, Ken Tanaka, Hiroshi Acute Med Surg Case Report BACKGROUND: The efficacy of steroid treatment for coronavirus disease (COVID‐19) is unknown. CASE PRESENTATION: A 67‐year‐old man was transported to our hospital due to impaired consciousness and respiratory failure. After admission, tracheal aspirate of the patient was harvested, and it tested positive for severe acute respiratory syndrome coronavirus 2 nucleic acid. He required veno‐venous extracorporeal membrane oxygenation to sustain his oxygenation. However, his respiratory failure did not improve for 20 days. On day 20 of admission, we started to use i.v. steroid therapy. On day 23, lung opacity on the chest X‐ray cleared and the patient’s oxygen saturation improved significantly. We successfully removed extracorporeal membrane oxygenation on day 27. CONCLUSION: Our case report encourages more future trials to evaluate the therapeutic use of i.v. steroid in severe COVID‐19‐induced acute respiratory distress syndrome. John Wiley and Sons Inc. 2020-09-23 /pmc/articles/PMC7511560/ /pubmed/33005428 http://dx.doi.org/10.1002/ams2.569 Text en © 2020 The Authors. Acute Medicine & Surgery published by John Wiley & Sons Australia, Ltd on behalf of Japanese Association for Acute Medicine This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Case Report
Kumakawa, Yasuaki
Hirano, Yohei
Sueyoshi, Koichiro
Ishihara, Tadashi
Kondo, Yutaka
Kawasaki, Takaaki
Takeuchi, Yuji
Nakamura, Yuki
Ishikawa, Kouhei
Watanabe, Yusuke
Saito, Wataru
Matsuda, Shigeru
Nakazawa, Takeshi
Sasaki, Shinichi
Okamoto, Ken
Tanaka, Hiroshi
Late i.v. steroid treatment for severe COVID‐19‐induced acute respiratory distress syndrome: a case report
title Late i.v. steroid treatment for severe COVID‐19‐induced acute respiratory distress syndrome: a case report
title_full Late i.v. steroid treatment for severe COVID‐19‐induced acute respiratory distress syndrome: a case report
title_fullStr Late i.v. steroid treatment for severe COVID‐19‐induced acute respiratory distress syndrome: a case report
title_full_unstemmed Late i.v. steroid treatment for severe COVID‐19‐induced acute respiratory distress syndrome: a case report
title_short Late i.v. steroid treatment for severe COVID‐19‐induced acute respiratory distress syndrome: a case report
title_sort late i.v. steroid treatment for severe covid‐19‐induced acute respiratory distress syndrome: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7511560/
https://www.ncbi.nlm.nih.gov/pubmed/33005428
http://dx.doi.org/10.1002/ams2.569
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