In vitro comparison of hydroxocobalamin (B12a) and the mitochondrial directed therapy by a succinate prodrug in a cellular model of cyanide poisoning

The objective of this study was to compare the use of hydroxocobalamin (B12a) and a succinate prodrug to evaluate for improvement in mitochondrial function in an in vitro model of cyanide poisoning. Peripheral blood mononuclear cells (PBMC) and human aortic smooth muscle cells (HASMC) incubated with...

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Detalles Bibliográficos
Autores principales: Owiredu, Shawn, Ranganathan, Abhay, Greenwood, John C., Piel, Sarah, Janowska, Joanna I., Eckmann, David M., Kelly, Matthew, Ehinger, Johannes K., Kilbaugh, Todd J., Jang, David H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7511654/
https://www.ncbi.nlm.nih.gov/pubmed/33005568
http://dx.doi.org/10.1016/j.toxrep.2020.09.002

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