Comparison of CRISPR/Cas Endonucleases for in vivo Retinal Gene Editing

CRISPR/Cas has opened the prospect of direct gene correction therapy for some inherited retinal diseases. Previous work has demonstrated the utility of adeno-associated virus (AAV) mediated delivery to retinal cells in vivo; however, with the expanding repertoire of CRISPR/Cas endonucleases, it is n...

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Detalles Bibliográficos
Autores principales: Li, Fan, Wing, Kristof, Wang, Jiang-Hui, Luu, Chi D., Bender, James A., Chen, Jinying, Wang, Qi, Lu, Qinyi, Nguyen Tran, Minh Thuan, Young, Kaylene M., Wong, Raymond C. B., Pébay, Alice, Cook, Anthony L., Hung, Sandy S. C., Liu, Guei-Sheung, Hewitt, Alex W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7511709/
https://www.ncbi.nlm.nih.gov/pubmed/33132845
http://dx.doi.org/10.3389/fncel.2020.570917

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