The Fragile X Mental Retardation Protein Regulates Striatal Medium Spiny Neuron Synapse Density and Dendritic Spine Morphology

The fragile X mental retardation protein (FMRP), an RNA-binding protein that mediates the transport, stability, and translation of hundreds of brain RNAs, is critically involved in regulating synaptic function. Loss of FMRP, as in fragile X syndrome (FXS), is a leading monogenic cause of autism and...

Descripción completa

Detalles Bibliográficos
Autores principales: Huebschman, Jessica L., Corona, Kitzia S., Guo, Yuhong, Smith, Laura N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7511717/
https://www.ncbi.nlm.nih.gov/pubmed/33013316
http://dx.doi.org/10.3389/fnmol.2020.00161

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7511717/
https://www.ncbi.nlm.nih.gov/pubmed/33013316
http://dx.doi.org/10.3389/fnmol.2020.00161

Ejemplares similares