Combining PARP and DNA-PK Inhibitors With Irradiation Inhibits HPV-Negative Head and Neck Cancer Squamous Carcinoma Growth

Novel targeted agents to inhibit DNA repair pathways to sensitize tumors to irradiation (IR) are being investigated as an alternative to chemoradiation for locally advanced human papilloma virus negative (HPV-negative) head and neck squamous cell carcinoma (HNSCC). Two well-characterized targets tha...

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Detalles Bibliográficos
Autores principales: Zeng, Ling, Boggs, Drexell Hunter, Xing, Chuan, Zhang, Zhuo, Anderson, Joshua C., Wajapeyee, Narendra, Veale, Chris, Bredel, Markus, Shi, Lewis Z., Bonner, James A., Willey, Christopher D., Yang, Eddy S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7511754/
https://www.ncbi.nlm.nih.gov/pubmed/33133138
http://dx.doi.org/10.3389/fgene.2020.01036

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7511754/
https://www.ncbi.nlm.nih.gov/pubmed/33133138
http://dx.doi.org/10.3389/fgene.2020.01036

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