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The Pseudomonas aeruginosa protease LasB directly activates IL-1β

BACKGROUND: Pulmonary damage by Pseudomonas aeruginosa during cystic fibrosis lung infection and ventilator-associated pneumonia is mediated both by pathogen virulence factors and host inflammation. Impaired immune function due to tissue damage and inflammation, coupled with pathogen multidrug resis...

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Detalles Bibliográficos
Autores principales:	Sun, Josh, LaRock, Doris L., Skowronski, Elaine A., Kimmey, Jacqueline M., Olson, Joshua, Jiang, Zhenze, O'Donoghue, Anthony J., Nizet, Victor, LaRock, Christopher N.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2020
Materias:	Research paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7511813/ https://www.ncbi.nlm.nih.gov/pubmed/32979835 http://dx.doi.org/10.1016/j.ebiom.2020.102984

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