Optimizing the Direction and Order of the Motion Unveiled the Ability of Conventional Monolayers of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes to Show Frequency-Dependent Enhancement of Contraction and Relaxation Motion

Contractility of the human heart increases as its beating rate is elevated, so-called positive force-frequency relationship; however, human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) have been reported to exert a negative force-frequency relationship. We tested the hypothesis t...

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Detalles Bibliográficos
Autores principales: Izumi-Nakaseko, Hiroko, Chiba, Koki, Hagiwara-Nagasawa, Mihoko, Satsuka, Ayano, Goto, Ai, Nunoi, Yoshio, Kambayashi, Ryuichi, Matsumoto, Akio, Takei, Yoshinori, Kanda, Yasunari, Naito, Atsuhiko T., Sugiyama, Atsushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7511828/
https://www.ncbi.nlm.nih.gov/pubmed/33015053
http://dx.doi.org/10.3389/fcell.2020.542562

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