Multiplex enzyme activity imaging by MALDI-IMS of substrate library conversions

Enzymes are fundamental to biological processes and involved in most pathologies. Here we demonstrate the concept of simultaneously mapping multiple enzyme activities (EA) by applying enzyme substrate libraries to tissue sections and analyzing their conversion by matrix-assisted laser desorption/ion...

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Detalles Bibliográficos
Autores principales: Klein, Oliver, Haeckel, Akvile, Reimer, Ulf, Nebrich, Grit, Schellenberger, Eyk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7511933/
https://www.ncbi.nlm.nih.gov/pubmed/32968143
http://dx.doi.org/10.1038/s41598-020-72436-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7511933/
https://www.ncbi.nlm.nih.gov/pubmed/32968143
http://dx.doi.org/10.1038/s41598-020-72436-2

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