Macrophage secretion of miR-106b-5p causes renin-dependent hypertension

Myeloid cells are known mediators of hypertension, but their role in initiating renin-induced hypertension has not been studied. Vitamin D deficiency causes pro-inflammatory macrophage infiltration in metabolic tissues and is linked to renin-mediated hypertension. We tested the hypothesis that impai...

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Detalles Bibliográficos
Autores principales: Oh, J., Matkovich, S. J., Riek, A. E., Bindom, S. M., Shao, J. S., Head, R. D., Barve, R. A., Sands, M. S., Carmeliet, G., Osei-Owusu, P., Knutsen, R. H., Zhang, H., Blumer, K. J., Nichols, C. G., Mecham, R. P., Baldán, Á, Benitez, B. A., Sequeira-Lopez, M. L., Gomez, R. A., Bernal-Mizrachi, C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7511948/
https://www.ncbi.nlm.nih.gov/pubmed/32968066
http://dx.doi.org/10.1038/s41467-020-18538-x

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