Efficient β-Carboline Alkaloid-Based Probe for Highly Sensitive Imaging of Endogenous Glutathione in Wheat Germ Tissues

Discriminative detection of GSH is achieved by employing a highly sensitive and selective fluorescent probe (KL-DN) that bears β-carboline alkaloid as a potential fluorophore and an azide group as the recognition unit. A rapid fluorescence off-on change is caused by special redox reaction; KL-DN has...

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Detalles Bibliográficos
Autores principales: Ji, Xiaohui, Zhang, Dan, Li, Le, Jin, Lingxia, Wu, Rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7512064/
https://www.ncbi.nlm.nih.gov/pubmed/33014063
http://dx.doi.org/10.1155/2020/8675784
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author Ji, Xiaohui
Zhang, Dan
Li, Le
Jin, Lingxia
Wu, Rui
author_facet Ji, Xiaohui
Zhang, Dan
Li, Le
Jin, Lingxia
Wu, Rui
author_sort Ji, Xiaohui
collection PubMed
description Discriminative detection of GSH is achieved by employing a highly sensitive and selective fluorescent probe (KL-DN) that bears β-carboline alkaloid as a potential fluorophore and an azide group as the recognition unit. A rapid fluorescence off-on change is caused by special redox reaction; KL-DN has the capability of monitoring endogenous GSH in wheat germ tissues, indicating that this probe holds great potential for biological applications in plant tissues.
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spelling pubmed-75120642020-10-02 Efficient β-Carboline Alkaloid-Based Probe for Highly Sensitive Imaging of Endogenous Glutathione in Wheat Germ Tissues Ji, Xiaohui Zhang, Dan Li, Le Jin, Lingxia Wu, Rui Int J Anal Chem Research Article Discriminative detection of GSH is achieved by employing a highly sensitive and selective fluorescent probe (KL-DN) that bears β-carboline alkaloid as a potential fluorophore and an azide group as the recognition unit. A rapid fluorescence off-on change is caused by special redox reaction; KL-DN has the capability of monitoring endogenous GSH in wheat germ tissues, indicating that this probe holds great potential for biological applications in plant tissues. Hindawi 2020-09-15 /pmc/articles/PMC7512064/ /pubmed/33014063 http://dx.doi.org/10.1155/2020/8675784 Text en Copyright © 2020 Xiaohui Ji et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Ji, Xiaohui
Zhang, Dan
Li, Le
Jin, Lingxia
Wu, Rui
Efficient β-Carboline Alkaloid-Based Probe for Highly Sensitive Imaging of Endogenous Glutathione in Wheat Germ Tissues
title Efficient β-Carboline Alkaloid-Based Probe for Highly Sensitive Imaging of Endogenous Glutathione in Wheat Germ Tissues
title_full Efficient β-Carboline Alkaloid-Based Probe for Highly Sensitive Imaging of Endogenous Glutathione in Wheat Germ Tissues
title_fullStr Efficient β-Carboline Alkaloid-Based Probe for Highly Sensitive Imaging of Endogenous Glutathione in Wheat Germ Tissues
title_full_unstemmed Efficient β-Carboline Alkaloid-Based Probe for Highly Sensitive Imaging of Endogenous Glutathione in Wheat Germ Tissues
title_short Efficient β-Carboline Alkaloid-Based Probe for Highly Sensitive Imaging of Endogenous Glutathione in Wheat Germ Tissues
title_sort efficient β-carboline alkaloid-based probe for highly sensitive imaging of endogenous glutathione in wheat germ tissues
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7512064/
https://www.ncbi.nlm.nih.gov/pubmed/33014063
http://dx.doi.org/10.1155/2020/8675784
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