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Protective Effect of Astragaloside IV on High Glucose-Induced Endothelial Dysfunction via Inhibition of P2X7R Dependent P38 MAPK Signaling Pathway

Vascular endothelial dysfunction is associated with increased mortality in patients with diabetes. Astragaloside IV (As-IV) is a bioactive saponin with therapeutic potential as an anti-inflammatory and antiendothelial dysfunction. However, the underlying mechanism for how As-IV ameliorated endotheli...

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Detalles Bibliográficos
Autores principales: Leng, Bin, Li, Cong, Sun, Yang, Zhao, Kun, Zhang, Ling, Lu, Mei-Li, Wang, Hong-Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7512101/
https://www.ncbi.nlm.nih.gov/pubmed/33014270
http://dx.doi.org/10.1155/2020/5070415