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Non-Hermitian Operator Modelling of Basic Cancer Cell Dynamics

We propose a dynamical system of tumor cells proliferation based on operatorial methods. The approach we propose is quantum-like: we use ladder and number operators to describe healthy and tumor cells birth and death, and the evolution is ruled by a non-hermitian Hamiltonian which includes, in a non...

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Detalles Bibliográficos
Autores principales: Bagarello, Fabio, Gargano, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7512787/
https://www.ncbi.nlm.nih.gov/pubmed/33265361
http://dx.doi.org/10.3390/e20040270
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author Bagarello, Fabio
Gargano, Francesco
author_facet Bagarello, Fabio
Gargano, Francesco
author_sort Bagarello, Fabio
collection PubMed
description We propose a dynamical system of tumor cells proliferation based on operatorial methods. The approach we propose is quantum-like: we use ladder and number operators to describe healthy and tumor cells birth and death, and the evolution is ruled by a non-hermitian Hamiltonian which includes, in a non reversible way, the basic biological mechanisms we consider for the system. We show that this approach is rather efficient in describing some processes of the cells. We further add some medical treatment, described by adding a suitable term in the Hamiltonian, which controls and limits the growth of tumor cells, and we propose an optimal approach to stop, and reverse, this growth.
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spelling pubmed-75127872020-11-09 Non-Hermitian Operator Modelling of Basic Cancer Cell Dynamics Bagarello, Fabio Gargano, Francesco Entropy (Basel) Article We propose a dynamical system of tumor cells proliferation based on operatorial methods. The approach we propose is quantum-like: we use ladder and number operators to describe healthy and tumor cells birth and death, and the evolution is ruled by a non-hermitian Hamiltonian which includes, in a non reversible way, the basic biological mechanisms we consider for the system. We show that this approach is rather efficient in describing some processes of the cells. We further add some medical treatment, described by adding a suitable term in the Hamiltonian, which controls and limits the growth of tumor cells, and we propose an optimal approach to stop, and reverse, this growth. MDPI 2018-04-11 /pmc/articles/PMC7512787/ /pubmed/33265361 http://dx.doi.org/10.3390/e20040270 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Bagarello, Fabio
Gargano, Francesco
Non-Hermitian Operator Modelling of Basic Cancer Cell Dynamics
title Non-Hermitian Operator Modelling of Basic Cancer Cell Dynamics
title_full Non-Hermitian Operator Modelling of Basic Cancer Cell Dynamics
title_fullStr Non-Hermitian Operator Modelling of Basic Cancer Cell Dynamics
title_full_unstemmed Non-Hermitian Operator Modelling of Basic Cancer Cell Dynamics
title_short Non-Hermitian Operator Modelling of Basic Cancer Cell Dynamics
title_sort non-hermitian operator modelling of basic cancer cell dynamics
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7512787/
https://www.ncbi.nlm.nih.gov/pubmed/33265361
http://dx.doi.org/10.3390/e20040270
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