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Spinal cannabinoid receptor 2 activation reduces hypersensitivity associated with bone cancer pain and improves the integrity of the blood–spinal cord barrier

BACKGROUND: Disruption of the blood–spinal cord barrier (BSCB) can facilitate inflammation that results in pain hypersensitivity. Proinflammatory cytokines produced by activated microglia and astrocytes damage the BSCB. This study aims to explore whether the BSCB is damaged in the bone cancer pain (...

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Detalles Bibliográficos
Autores principales:	Wang, Chenchen, Xu, Ke, Wang, Yu, Mao, Yanting, Huang, Yulin, Liang, Ying, Liu, Yue, Hao, Jing, Gu, Xiaoping, Ma, Zhengliang, Sun, Yu'e
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7513263/ https://www.ncbi.nlm.nih.gov/pubmed/32796132 http://dx.doi.org/10.1136/rapm-2019-101262

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