HSD1787, a Tetrahydro-3H-Pyrazolo[4,3-f]Quinoline Compound Synthesized via Povarov Reaction, Potently Inhibits Proliferation of Cancer Cell Lines at Nanomolar Concentrations

[Image: see text] Multicomponent reaction (MCR) is often used to rapidly assemble complex compounds for drug screening. Povarov MCR has been used to prepare a new library containing tetrahydro-3H-pyrazolo[4,3-f]quinoline core and the library tested against MDA-MB-231 (a triple-negative breast cancer...

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Detalles Bibliográficos
Autores principales: Dayal, Neetu, Wang, Modi, Sintim, Herman O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7513343/
https://www.ncbi.nlm.nih.gov/pubmed/32984700
http://dx.doi.org/10.1021/acsomega.0c03001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7513343/
https://www.ncbi.nlm.nih.gov/pubmed/32984700
http://dx.doi.org/10.1021/acsomega.0c03001

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