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OROFACIAL CLEFTS AND CARDIOVASCULAR RISK AND DISEASES: THE CAUSAL RELATIONSHIP AND ASSOCIATIONS

There is a complex interplay between orofacial clefts (OFCs) or cleft of the lip and palate and cardiovascular risk factors and cardiac diseases. The presence of maternal cardiovascular risk factors serves as a potent predisposing factor to the development of OFCs during foetal development in additi...

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Detalles Bibliográficos
Autores principales: Nwaze, C.E., Adebayo, O., Adeoye, A.M., Akinmoladun, V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Association of Resident Doctors (ARD), University College Hospital, Ibadan 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7513382/
https://www.ncbi.nlm.nih.gov/pubmed/33071693
Descripción
Sumario:There is a complex interplay between orofacial clefts (OFCs) or cleft of the lip and palate and cardiovascular risk factors and cardiac diseases. The presence of maternal cardiovascular risk factors serves as a potent predisposing factor to the development of OFCs during foetal development in addition to the fact that various congenital anomalies are associated with OFCs either in syndromic or non-syndrome relationship. This article narratively explores this complex interplay, which is not uncommon.