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Citrulline, A Potential Biomarker of Radiation-Induced Small Intestine Damage
Radiation damage assessment of the small intestine is important in nuclear accidents or routine radiotherapy of abdominal tumors. This article reviews the clinical symptoms and molecular mechanisms of radiation-induced small intestinal damage and summarizes recent research on biomarkers of such dama...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7513408/ https://www.ncbi.nlm.nih.gov/pubmed/33013253 http://dx.doi.org/10.1177/1559325820962341 |
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author | Ye, Fei Ning, Jing Fardous, Zeenath Katsube, Takanori Li, Qiang Wang, Bing |
author_facet | Ye, Fei Ning, Jing Fardous, Zeenath Katsube, Takanori Li, Qiang Wang, Bing |
author_sort | Ye, Fei |
collection | PubMed |
description | Radiation damage assessment of the small intestine is important in nuclear accidents or routine radiotherapy of abdominal tumors. This article reviews the clinical symptoms and molecular mechanisms of radiation-induced small intestinal damage and summarizes recent research on biomarkers of such damage. Citrulline is the most promising biomarker for the evaluation of radiation-induced small intestinal damage caused by radiotherapy and nuclear accidents. This article also summarizes the factors influencing plasma citrulline measurement investigated in the latest research, as well as new findings on the concentration of citrulline in saliva and urine after different types of radiation. |
format | Online Article Text |
id | pubmed-7513408 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | SAGE Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-75134082020-10-01 Citrulline, A Potential Biomarker of Radiation-Induced Small Intestine Damage Ye, Fei Ning, Jing Fardous, Zeenath Katsube, Takanori Li, Qiang Wang, Bing Dose Response Review Radiation damage assessment of the small intestine is important in nuclear accidents or routine radiotherapy of abdominal tumors. This article reviews the clinical symptoms and molecular mechanisms of radiation-induced small intestinal damage and summarizes recent research on biomarkers of such damage. Citrulline is the most promising biomarker for the evaluation of radiation-induced small intestinal damage caused by radiotherapy and nuclear accidents. This article also summarizes the factors influencing plasma citrulline measurement investigated in the latest research, as well as new findings on the concentration of citrulline in saliva and urine after different types of radiation. SAGE Publications 2020-09-22 /pmc/articles/PMC7513408/ /pubmed/33013253 http://dx.doi.org/10.1177/1559325820962341 Text en © The Author(s) 2020 https://creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage). |
spellingShingle | Review Ye, Fei Ning, Jing Fardous, Zeenath Katsube, Takanori Li, Qiang Wang, Bing Citrulline, A Potential Biomarker of Radiation-Induced Small Intestine Damage |
title | Citrulline, A Potential Biomarker of Radiation-Induced Small
Intestine Damage |
title_full | Citrulline, A Potential Biomarker of Radiation-Induced Small
Intestine Damage |
title_fullStr | Citrulline, A Potential Biomarker of Radiation-Induced Small
Intestine Damage |
title_full_unstemmed | Citrulline, A Potential Biomarker of Radiation-Induced Small
Intestine Damage |
title_short | Citrulline, A Potential Biomarker of Radiation-Induced Small
Intestine Damage |
title_sort | citrulline, a potential biomarker of radiation-induced small
intestine damage |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7513408/ https://www.ncbi.nlm.nih.gov/pubmed/33013253 http://dx.doi.org/10.1177/1559325820962341 |
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