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GraphAligner: rapid and versatile sequence-to-graph alignment

Genome graphs can represent genetic variation and sequence uncertainty. Aligning sequences to genome graphs is key to many applications, including error correction, genome assembly, and genotyping of variants in a pangenome graph. Yet, so far, this step is often prohibitively slow. We present GraphA...

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Detalles Bibliográficos
Autores principales: Rautiainen, Mikko, Marschall, Tobias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7513500/
https://www.ncbi.nlm.nih.gov/pubmed/32972461
http://dx.doi.org/10.1186/s13059-020-02157-2

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