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Hybrid semiparametric systems for quantitative sequence-activity modeling of synthetic biological parts
Predicting the activity of modified biological parts is difficult due to the typically large size of nucleotide sequences, resulting in combinatorial designs that suffer from the “curse of dimensionality” problem. Mechanistic design methods are often limited by knowledge availability. Empirical meth...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7513808/ https://www.ncbi.nlm.nih.gov/pubmed/32995518 http://dx.doi.org/10.1093/synbio/ysy010 |