The regulation of Net1/Cdc14 by the Hog1 MAPK upon osmostress unravels a new mechanism regulating mitosis

During evolution, cells have developed a plethora of mechanisms to optimize survival in a changing and unpredictable environment. In this regard, they have evolved networks that include environmental sensors, signaling transduction molecules and response mechanisms. Hog1 (yeast) and p38 (mammals) st...

Descripción completa

Detalles Bibliográficos
Autores principales: Jiménez, Javier, Queralt, Ethel, Posas, Francesc, de Nadal, Eulàlia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7513861/
https://www.ncbi.nlm.nih.gov/pubmed/32794416
http://dx.doi.org/10.1080/15384101.2020.1804222
_version_ 1783586464924172288
author Jiménez, Javier
Queralt, Ethel
Posas, Francesc
de Nadal, Eulàlia
author_facet Jiménez, Javier
Queralt, Ethel
Posas, Francesc
de Nadal, Eulàlia
author_sort Jiménez, Javier
collection PubMed
description During evolution, cells have developed a plethora of mechanisms to optimize survival in a changing and unpredictable environment. In this regard, they have evolved networks that include environmental sensors, signaling transduction molecules and response mechanisms. Hog1 (yeast) and p38 (mammals) stress-activated protein kinases (SAPKs) are activated upon stress and they drive a full collection of cell adaptive responses aimed to maximize survival. SAPKs are extensively used to learn about the mechanisms through which cells adapt to changing environments. In addition to regulating gene expression and metabolism, SAPKs control cell cycle progression. In this review, we will discuss the latest findings related to the SAPK-driven regulation of mitosis upon osmostress in yeast.
format Online
Article
Text
id pubmed-7513861
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Taylor & Francis
record_format MEDLINE/PubMed
spelling pubmed-75138612020-10-01 The regulation of Net1/Cdc14 by the Hog1 MAPK upon osmostress unravels a new mechanism regulating mitosis Jiménez, Javier Queralt, Ethel Posas, Francesc de Nadal, Eulàlia Cell Cycle Review During evolution, cells have developed a plethora of mechanisms to optimize survival in a changing and unpredictable environment. In this regard, they have evolved networks that include environmental sensors, signaling transduction molecules and response mechanisms. Hog1 (yeast) and p38 (mammals) stress-activated protein kinases (SAPKs) are activated upon stress and they drive a full collection of cell adaptive responses aimed to maximize survival. SAPKs are extensively used to learn about the mechanisms through which cells adapt to changing environments. In addition to regulating gene expression and metabolism, SAPKs control cell cycle progression. In this review, we will discuss the latest findings related to the SAPK-driven regulation of mitosis upon osmostress in yeast. Taylor & Francis 2020-08-14 /pmc/articles/PMC7513861/ /pubmed/32794416 http://dx.doi.org/10.1080/15384101.2020.1804222 Text en © 2020 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License (http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) ), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited, and is not altered, transformed, or built upon in any way.
spellingShingle Review
Jiménez, Javier
Queralt, Ethel
Posas, Francesc
de Nadal, Eulàlia
The regulation of Net1/Cdc14 by the Hog1 MAPK upon osmostress unravels a new mechanism regulating mitosis
title The regulation of Net1/Cdc14 by the Hog1 MAPK upon osmostress unravels a new mechanism regulating mitosis
title_full The regulation of Net1/Cdc14 by the Hog1 MAPK upon osmostress unravels a new mechanism regulating mitosis
title_fullStr The regulation of Net1/Cdc14 by the Hog1 MAPK upon osmostress unravels a new mechanism regulating mitosis
title_full_unstemmed The regulation of Net1/Cdc14 by the Hog1 MAPK upon osmostress unravels a new mechanism regulating mitosis
title_short The regulation of Net1/Cdc14 by the Hog1 MAPK upon osmostress unravels a new mechanism regulating mitosis
title_sort regulation of net1/cdc14 by the hog1 mapk upon osmostress unravels a new mechanism regulating mitosis
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7513861/
https://www.ncbi.nlm.nih.gov/pubmed/32794416
http://dx.doi.org/10.1080/15384101.2020.1804222
work_keys_str_mv AT jimenezjavier theregulationofnet1cdc14bythehog1mapkuponosmostressunravelsanewmechanismregulatingmitosis
AT queraltethel theregulationofnet1cdc14bythehog1mapkuponosmostressunravelsanewmechanismregulatingmitosis
AT posasfrancesc theregulationofnet1cdc14bythehog1mapkuponosmostressunravelsanewmechanismregulatingmitosis
AT denadaleulalia theregulationofnet1cdc14bythehog1mapkuponosmostressunravelsanewmechanismregulatingmitosis
AT jimenezjavier regulationofnet1cdc14bythehog1mapkuponosmostressunravelsanewmechanismregulatingmitosis
AT queraltethel regulationofnet1cdc14bythehog1mapkuponosmostressunravelsanewmechanismregulatingmitosis
AT posasfrancesc regulationofnet1cdc14bythehog1mapkuponosmostressunravelsanewmechanismregulatingmitosis
AT denadaleulalia regulationofnet1cdc14bythehog1mapkuponosmostressunravelsanewmechanismregulatingmitosis

Ejemplares similares