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The functions of kinesin and kinesin-related proteins in eukaryotes

Kinesins constitute a superfamily of ATP-driven microtubule motor enzymes that convert the chemical energy of ATP hydrolysis into mechanical work along microtubule tracks. Kinesins are found in all eukaryotic organisms and are essential to all eukaryotic cells, involved in diverse cellular functions...

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Detalles Bibliográficos
Autores principales: Ali, Iftikhar, Yang, Wei-Cai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7513868/
https://www.ncbi.nlm.nih.gov/pubmed/32842864
http://dx.doi.org/10.1080/19336918.2020.1810939
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author Ali, Iftikhar
Yang, Wei-Cai
author_facet Ali, Iftikhar
Yang, Wei-Cai
author_sort Ali, Iftikhar
collection PubMed
description Kinesins constitute a superfamily of ATP-driven microtubule motor enzymes that convert the chemical energy of ATP hydrolysis into mechanical work along microtubule tracks. Kinesins are found in all eukaryotic organisms and are essential to all eukaryotic cells, involved in diverse cellular functions such as microtubule dynamics and morphogenesis, chromosome segregation, spindle formation and elongation and transport of organelles. In this review, we explore recently reported functions of kinesins in eukaryotes and compare their specific cargoes in both plant and animal kingdoms to understand the possible roles of uncharacterized motors in a kingdom based on their reported functions in other kingdoms.
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spelling pubmed-75138682020-10-01 The functions of kinesin and kinesin-related proteins in eukaryotes Ali, Iftikhar Yang, Wei-Cai Cell Adh Migr Review Kinesins constitute a superfamily of ATP-driven microtubule motor enzymes that convert the chemical energy of ATP hydrolysis into mechanical work along microtubule tracks. Kinesins are found in all eukaryotic organisms and are essential to all eukaryotic cells, involved in diverse cellular functions such as microtubule dynamics and morphogenesis, chromosome segregation, spindle formation and elongation and transport of organelles. In this review, we explore recently reported functions of kinesins in eukaryotes and compare their specific cargoes in both plant and animal kingdoms to understand the possible roles of uncharacterized motors in a kingdom based on their reported functions in other kingdoms. Taylor & Francis 2020-08-25 /pmc/articles/PMC7513868/ /pubmed/32842864 http://dx.doi.org/10.1080/19336918.2020.1810939 Text en © 2020 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review
Ali, Iftikhar
Yang, Wei-Cai
The functions of kinesin and kinesin-related proteins in eukaryotes
title The functions of kinesin and kinesin-related proteins in eukaryotes
title_full The functions of kinesin and kinesin-related proteins in eukaryotes
title_fullStr The functions of kinesin and kinesin-related proteins in eukaryotes
title_full_unstemmed The functions of kinesin and kinesin-related proteins in eukaryotes
title_short The functions of kinesin and kinesin-related proteins in eukaryotes
title_sort functions of kinesin and kinesin-related proteins in eukaryotes
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7513868/
https://www.ncbi.nlm.nih.gov/pubmed/32842864
http://dx.doi.org/10.1080/19336918.2020.1810939
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