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ADAM17 cytoplasmic domain modulates Thioredoxin-1 conformation and activity

The activity of Thioredoxin-1 (Trx-1) is adjusted by the balance of its monomeric, active and its dimeric, inactive state. The regulation of this balance is not completely understood. We have previously shown that the cytoplasmic domain of the transmembrane protein A Disintegrin And Metalloprotease...

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Detalles Bibliográficos
Autores principales: e Costa, Rute A.P., Granato, Daniela C., Trino, Luciana D., Yokoo, Sami, Carnielli, Carolina M., Kawahara, Rebeca, Domingues, Romênia R., Pauletti, Bianca Alves, Neves, Leandro Xavier, Santana, Aline G., Paulo, Joao A., Aragão, Annelize Z.B., Heleno Batista, Fernanda Aparecida, Migliorini Figueira, Ana Carolina, Laurindo, Francisco R.M., Fernandes, Denise, Hansen, Hinrich P., Squina, Fabio, Gygi, Steven P., Paes Leme, Adriana F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7513893/
https://www.ncbi.nlm.nih.gov/pubmed/33011677
http://dx.doi.org/10.1016/j.redox.2020.101735