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COVID19: an announced pandemic

A severe upper respiratory tract syndrome caused by the new coronavirus has now spread to the entire world as a highly contagious pandemic. The large scale explosion of the disease is conventionally traced back to January of this year in the Chinese province of Hubei, the wet markets of the principa...

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Autores principales: Platto, Sara, Xue, Tongtong, Carafoli, Ernesto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7513903/
https://www.ncbi.nlm.nih.gov/pubmed/32973152
http://dx.doi.org/10.1038/s41419-020-02995-9
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author Platto, Sara
Xue, Tongtong
Carafoli, Ernesto
author_facet Platto, Sara
Xue, Tongtong
Carafoli, Ernesto
author_sort Platto, Sara
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description A severe upper respiratory tract syndrome caused by the new coronavirus has now spread to the entire world as a highly contagious pandemic. The large scale explosion of the disease is conventionally traced back to January of this year in the Chinese province of Hubei, the wet markets of the principal city of Wuhan being assumed to have been the specific causative locus of the sudden explosion of the infection. A number of findings that are now coming to light show that this interpretation of the origin and history of the pandemic is overly simplified. A number of variants of the coronavirus would in principle have had the ability to initiate the pandemic well before January of this year. However, even if the COVID-19 had become, so to say, ready, conditions in the local environment would have had to prevail to induce the loss of the biodiversity’s “dilution effect” that kept the virus under control, favoring its spillover from its bat reservoir to the human target. In the absence of these appropriate conditions only abortive attempts to initiate the pandemic could possibly occur: a number of them did indeed occur in China, and probably elsewhere as well. These conditions were unfortunately present at the wet marked in Wuhan at the end of last year.
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spelling pubmed-75139032020-09-25 COVID19: an announced pandemic Platto, Sara Xue, Tongtong Carafoli, Ernesto Cell Death Dis Review Article A severe upper respiratory tract syndrome caused by the new coronavirus has now spread to the entire world as a highly contagious pandemic. The large scale explosion of the disease is conventionally traced back to January of this year in the Chinese province of Hubei, the wet markets of the principal city of Wuhan being assumed to have been the specific causative locus of the sudden explosion of the infection. A number of findings that are now coming to light show that this interpretation of the origin and history of the pandemic is overly simplified. A number of variants of the coronavirus would in principle have had the ability to initiate the pandemic well before January of this year. However, even if the COVID-19 had become, so to say, ready, conditions in the local environment would have had to prevail to induce the loss of the biodiversity’s “dilution effect” that kept the virus under control, favoring its spillover from its bat reservoir to the human target. In the absence of these appropriate conditions only abortive attempts to initiate the pandemic could possibly occur: a number of them did indeed occur in China, and probably elsewhere as well. These conditions were unfortunately present at the wet marked in Wuhan at the end of last year. Nature Publishing Group UK 2020-09-24 /pmc/articles/PMC7513903/ /pubmed/32973152 http://dx.doi.org/10.1038/s41419-020-02995-9 Text en © The Author(s) 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Review Article
Platto, Sara
Xue, Tongtong
Carafoli, Ernesto
COVID19: an announced pandemic
title COVID19: an announced pandemic
title_full COVID19: an announced pandemic
title_fullStr COVID19: an announced pandemic
title_full_unstemmed COVID19: an announced pandemic
title_short COVID19: an announced pandemic
title_sort covid19: an announced pandemic
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7513903/
https://www.ncbi.nlm.nih.gov/pubmed/32973152
http://dx.doi.org/10.1038/s41419-020-02995-9
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