Factors related to asymptomatic or severe COVID-19 infection

The factors that may contribute to a COVID-19 patient remaining in the asymptomatic stage, or to the infection evolving into the more serious stages are examined. In particular, we refer to the TMPRSS2 expression profile, balance of androgen and estrogen, blood group-A and/or B, nonsynonymous mutati...

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Detalles Bibliográficos
Autores principales: Mayoral, Eduardo Pérez-Campos, Hernández-Huerta, María Teresa, Pérez-Campos Mayoral, Laura, Matias-Cervantes, Carlos Alberto, Mayoral-Andrade, Gabriel, Barrios, Luis Ángel Laguna, Pérez-Campos, Eduardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7513914/
https://www.ncbi.nlm.nih.gov/pubmed/33254487
http://dx.doi.org/10.1016/j.mehy.2020.110296
Descripción
Sumario:The factors that may contribute to a COVID-19 patient remaining in the asymptomatic stage, or to the infection evolving into the more serious stages are examined. In particular, we refer to the TMPRSS2 expression profile, balance of androgen and estrogen, blood group-A and/or B, nonsynonymous mutations in ORF3, and proteins NS7b and NS8 in SARS-CoV-2. Also, we review other factors related to the susceptibility and pathogenicity of SARS-CoV-2.

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