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A rapid absorbance-based growth assay to screen the toxicity of oligomer Aβ(42) and protect against cell death in yeast
Multiple lines of evidence show that soluble oligomer forms of amyloid β protein (Aβ(42)) are the most neurotoxic species in the brain and correlates with the degree of neuronal loss and cognitive deficit in Alzheimer’s disease. Although many studies have used mammalian cells to investigate oligomer...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Wolters Kluwer - Medknow
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7513978/ https://www.ncbi.nlm.nih.gov/pubmed/32246642 http://dx.doi.org/10.4103/1673-5374.280318 |