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Linker region is required for efficient nuclear localization of polynucleotide kinase phosphatase
Polynucleotide kinase phosphatase (PNKP) is a DNA repair factor with dual enzymatic functions, i.e., phosphorylation of 5’-end and dephosphorylation of 3’-end, which are prerequisites for DNA ligation and, thus, is involved in multiple DNA repair pathways, i.e., base excision repair, single-strand b...
Autores principales: | Tsukada, Kaima, Matsumoto, Yoshihisa, Shimada, Mikio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7514006/ https://www.ncbi.nlm.nih.gov/pubmed/32970693 http://dx.doi.org/10.1371/journal.pone.0239404 |
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