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Limbus misrepresentation in parametric eye models

PURPOSE: To assess the axial, radial and tangential limbus position misrepresentation when parametric models are used to represent the cornea and the sclera. METHODS: This retrospective study included 135 subjects aged 22 to 65 years (36.5 mean ±9.8 STD), 71 females and 64 males. Topography measurem...

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Autores principales: Moore, Joshua, Shu, Xuhan, Lopes, Bernardo T., Wu, Richard, Abass, Ahmed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7514007/
https://www.ncbi.nlm.nih.gov/pubmed/32970690
http://dx.doi.org/10.1371/journal.pone.0236096
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author Moore, Joshua
Shu, Xuhan
Lopes, Bernardo T.
Wu, Richard
Abass, Ahmed
author_facet Moore, Joshua
Shu, Xuhan
Lopes, Bernardo T.
Wu, Richard
Abass, Ahmed
author_sort Moore, Joshua
collection PubMed
description PURPOSE: To assess the axial, radial and tangential limbus position misrepresentation when parametric models are used to represent the cornea and the sclera. METHODS: This retrospective study included 135 subjects aged 22 to 65 years (36.5 mean ±9.8 STD), 71 females and 64 males. Topography measurements were taken using an Eye Surface Profiler topographer and processed by a custom-built MATLAB code. Eye surfaces were freed from edge-effect artefacts and fitted to spherical, conic and biconic models. RESULTS: When comparing the radial position of the limbus, average errors of -0.83±0.19mm, -0.76±0.20mm and -0.69±0.20mm were observed within the right eye population for the spherical, conic and biconic models fitted up to 5mm. For the same fitting radius, the average fitting errors were -0.86±0.23mm, -0.78±0.23mm and -0.73±0.23mm for the spherical, conic and biconic models respectively within the left eye population. For the whole cornea fit, the average errors were -0.27±0.12mm and -0.28±0.13mm for the spherical models, -0.02±0.29mm and -0.05±0.27mm for the conic models, and -0.22±0.16mm and 0.24±0.17mm for the biconic models in the right and left eye populations respectively. CONCLUSIONS: Through the use of spherical, conic and biconic parametric modelling methods, the eye’s limbus is being mislocated. Additionally, it is evident that the magnitude of fitting error associated with the sclera may be propagating through the other components of the eye. This suggests that a corneal nonparametric model may be necessary to improve the representation of the limbus.
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spelling pubmed-75140072020-10-01 Limbus misrepresentation in parametric eye models Moore, Joshua Shu, Xuhan Lopes, Bernardo T. Wu, Richard Abass, Ahmed PLoS One Research Article PURPOSE: To assess the axial, radial and tangential limbus position misrepresentation when parametric models are used to represent the cornea and the sclera. METHODS: This retrospective study included 135 subjects aged 22 to 65 years (36.5 mean ±9.8 STD), 71 females and 64 males. Topography measurements were taken using an Eye Surface Profiler topographer and processed by a custom-built MATLAB code. Eye surfaces were freed from edge-effect artefacts and fitted to spherical, conic and biconic models. RESULTS: When comparing the radial position of the limbus, average errors of -0.83±0.19mm, -0.76±0.20mm and -0.69±0.20mm were observed within the right eye population for the spherical, conic and biconic models fitted up to 5mm. For the same fitting radius, the average fitting errors were -0.86±0.23mm, -0.78±0.23mm and -0.73±0.23mm for the spherical, conic and biconic models respectively within the left eye population. For the whole cornea fit, the average errors were -0.27±0.12mm and -0.28±0.13mm for the spherical models, -0.02±0.29mm and -0.05±0.27mm for the conic models, and -0.22±0.16mm and 0.24±0.17mm for the biconic models in the right and left eye populations respectively. CONCLUSIONS: Through the use of spherical, conic and biconic parametric modelling methods, the eye’s limbus is being mislocated. Additionally, it is evident that the magnitude of fitting error associated with the sclera may be propagating through the other components of the eye. This suggests that a corneal nonparametric model may be necessary to improve the representation of the limbus. Public Library of Science 2020-09-24 /pmc/articles/PMC7514007/ /pubmed/32970690 http://dx.doi.org/10.1371/journal.pone.0236096 Text en © 2020 Moore et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Moore, Joshua
Shu, Xuhan
Lopes, Bernardo T.
Wu, Richard
Abass, Ahmed
Limbus misrepresentation in parametric eye models
title Limbus misrepresentation in parametric eye models
title_full Limbus misrepresentation in parametric eye models
title_fullStr Limbus misrepresentation in parametric eye models
title_full_unstemmed Limbus misrepresentation in parametric eye models
title_short Limbus misrepresentation in parametric eye models
title_sort limbus misrepresentation in parametric eye models
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7514007/
https://www.ncbi.nlm.nih.gov/pubmed/32970690
http://dx.doi.org/10.1371/journal.pone.0236096
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