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Multiplex in situ hybridization within a single transcript: RNAscope reveals dystrophin mRNA dynamics
Dystrophin plays a vital role in maintaining muscle health, yet low mRNA expression, lengthy transcription time and the limitations of traditional in-situ hybridization (ISH) methodologies mean that the dynamics of dystrophin transcription remain poorly understood. RNAscope is highly sensitive ISH m...
Autores principales: | Hildyard, John C. W., Rawson, Faye, Wells, Dominic J., Piercy, Richard J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7514052/ https://www.ncbi.nlm.nih.gov/pubmed/32970731 http://dx.doi.org/10.1371/journal.pone.0239467 |
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