Cargando…
Dynamical Behavior of β-Lactamases and Penicillin- Binding Proteins in Different Functional States and Its Potential Role in Evolution
β-Lactamases are enzymes produced by bacteria to hydrolyze β-lactam-based antibiotics, and pose serious threat to public health through related antibiotic resistance. Class A β-lactamases are structurally and functionally related to penicillin-binding proteins (PBPs). Despite the extensive studies o...
Autores principales: | Wang, Feng, Zhou, Hongyu, Wang, Xinlei, Tao, Peng |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7514474/ http://dx.doi.org/10.3390/e21111130 |
Ejemplares similares
-
Machine Learning Classification Model for Functional Binding Modes of TEM-1 β-Lactamase
por: Wang, Feng, et al.
Publicado: (2019) -
Structural basis of metallo-β-lactamase, serine-β-lactamase and penicillin-binding protein inhibition by cyclic boronates
por: Brem, Jürgen, et al.
Publicado: (2016) -
Penicillin-Binding Proteins, β-Lactamases, and β-Lactamase Inhibitors in β-Lactam-Producing Actinobacteria: Self-Resistance Mechanisms
por: Martin, Juan F., et al.
Publicado: (2022) -
Penicillin Binding Proteins and β-Lactamases of Mycobacterium tuberculosis: Reexamination of the Historical Paradigm
por: Kumar, Gaurav, et al.
Publicado: (2022) -
Human metallo-β-lactamase enzymes degrade penicillin
por: Diene, Seydina M., et al.
Publicado: (2019)