Asynchronous Control of P300-Based Brain–Computer Interfaces Using Sample Entropy

Brain–computer interfaces (BCI) have traditionally worked using synchronous paradigms. In recent years, much effort has been put into reaching asynchronous management, providing users with the ability to decide when a command should be selected. However, to the best of our knowledge, entropy metrics have not yet been explored. The present study has a twofold purpose: (i) to characterize both control and non-control states by examining the regularity of electroencephalography (EEG) signals; and (ii) to assess the efficacy of a scaled version of the sample entropy algorithm to provide asynchronous control for BCI systems. Ten healthy subjects participated in the study, who were asked to spell words through a visual oddball-based paradigm, attending (i.e., control) and ignoring (i.e., non-control) the stimuli. An optimization stage was performed for determining a common combination of hyperparameters for all subjects. Afterwards, these values were used to discern between both states using a linear classifier. Results show that control signals are more complex and irregular than non-control ones, reaching an average accuracy of [Formula: see text] in classification. In conclusion, the present study demonstrates that the proposed framework is useful in monitoring the attention of a user, and granting the asynchrony of the BCI system.