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Aging Modulates the Resting Brain after a Memory Task: A Validation Study from Multivariate Models

Recent work has demonstrated that aging modulates the resting brain. However, the study of these modulations after cognitive practice, resulting from a memory task, has been scarce. This work aims at examining age-related changes in the functional reorganization of the resting brain after cognitive...

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Autores principales: Artola, Garazi, Isusquiza, Erik, Errarte, Ane, Barrenechea, Maitane, Alberdi, Ane, Hernández-Lorca, María, Solesio-Jofre, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7514899/
https://www.ncbi.nlm.nih.gov/pubmed/33267125
http://dx.doi.org/10.3390/e21040411
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author Artola, Garazi
Isusquiza, Erik
Errarte, Ane
Barrenechea, Maitane
Alberdi, Ane
Hernández-Lorca, María
Solesio-Jofre, Elena
author_facet Artola, Garazi
Isusquiza, Erik
Errarte, Ane
Barrenechea, Maitane
Alberdi, Ane
Hernández-Lorca, María
Solesio-Jofre, Elena
author_sort Artola, Garazi
collection PubMed
description Recent work has demonstrated that aging modulates the resting brain. However, the study of these modulations after cognitive practice, resulting from a memory task, has been scarce. This work aims at examining age-related changes in the functional reorganization of the resting brain after cognitive training, namely, neuroplasticity, by means of the most innovative tools for data analysis. To this end, electroencephalographic activity was recorded in 34 young and 38 older participants. Different methods for data analyses, including frequency, time-frequency and machine learning-based prediction models were conducted. Results showed reductions in Alpha power in old compared to young adults in electrodes placed over posterior and anterior areas of the brain. Moreover, young participants showed Alpha power increases after task performance, while their older counterparts exhibited a more invariant pattern of results. These results were significant in the 140–160 s time window in electrodes placed over anterior regions of the brain. Machine learning analyses were able to accurately classify participants by age, but failed to predict whether resting state scans took place before or after the memory task. These findings greatly contribute to the development of multivariate tools for electroencephalogram (EEG) data analysis and improve our understanding of age-related changes in the functional reorganization of the resting brain.
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spelling pubmed-75148992020-11-09 Aging Modulates the Resting Brain after a Memory Task: A Validation Study from Multivariate Models Artola, Garazi Isusquiza, Erik Errarte, Ane Barrenechea, Maitane Alberdi, Ane Hernández-Lorca, María Solesio-Jofre, Elena Entropy (Basel) Article Recent work has demonstrated that aging modulates the resting brain. However, the study of these modulations after cognitive practice, resulting from a memory task, has been scarce. This work aims at examining age-related changes in the functional reorganization of the resting brain after cognitive training, namely, neuroplasticity, by means of the most innovative tools for data analysis. To this end, electroencephalographic activity was recorded in 34 young and 38 older participants. Different methods for data analyses, including frequency, time-frequency and machine learning-based prediction models were conducted. Results showed reductions in Alpha power in old compared to young adults in electrodes placed over posterior and anterior areas of the brain. Moreover, young participants showed Alpha power increases after task performance, while their older counterparts exhibited a more invariant pattern of results. These results were significant in the 140–160 s time window in electrodes placed over anterior regions of the brain. Machine learning analyses were able to accurately classify participants by age, but failed to predict whether resting state scans took place before or after the memory task. These findings greatly contribute to the development of multivariate tools for electroencephalogram (EEG) data analysis and improve our understanding of age-related changes in the functional reorganization of the resting brain. MDPI 2019-04-17 /pmc/articles/PMC7514899/ /pubmed/33267125 http://dx.doi.org/10.3390/e21040411 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Artola, Garazi
Isusquiza, Erik
Errarte, Ane
Barrenechea, Maitane
Alberdi, Ane
Hernández-Lorca, María
Solesio-Jofre, Elena
Aging Modulates the Resting Brain after a Memory Task: A Validation Study from Multivariate Models
title Aging Modulates the Resting Brain after a Memory Task: A Validation Study from Multivariate Models
title_full Aging Modulates the Resting Brain after a Memory Task: A Validation Study from Multivariate Models
title_fullStr Aging Modulates the Resting Brain after a Memory Task: A Validation Study from Multivariate Models
title_full_unstemmed Aging Modulates the Resting Brain after a Memory Task: A Validation Study from Multivariate Models
title_short Aging Modulates the Resting Brain after a Memory Task: A Validation Study from Multivariate Models
title_sort aging modulates the resting brain after a memory task: a validation study from multivariate models
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7514899/
https://www.ncbi.nlm.nih.gov/pubmed/33267125
http://dx.doi.org/10.3390/e21040411
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