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The causal effect of obesity on prediabetes and insulin resistance reveals the important role of adipose tissue in insulin resistance

Reverse causality has made it difficult to establish the causal directions between obesity and prediabetes and obesity and insulin resistance. To disentangle whether obesity causally drives prediabetes and insulin resistance already in non-diabetic individuals, we utilized the UK Biobank and METSIM...

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Detalles Bibliográficos
Autores principales:	Miao, Zong, Alvarez, Marcus, Ko, Arthur, Bhagat, Yash, Rahmani, Elior, Jew, Brandon, Heinonen, Sini, Muñoz-Hernandez, Linda Liliana, Herrera-Hernandez, Miguel, Aguilar-Salinas, Carlos, Tusie-Luna, Teresa, Mohlke, Karen L., Laakso, Markku, Pietiläinen, Kirsi H., Halperin, Eran, Pajukanta, Päivi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7515203/ https://www.ncbi.nlm.nih.gov/pubmed/32925908 http://dx.doi.org/10.1371/journal.pgen.1009018

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