Pathogenic Autoimmunity in Atherosclerosis Evolves From Initially Protective Apolipoprotein B(100)–Reactive CD4(+) T-Regulatory Cells

Throughout the inflammatory response that accompanies atherosclerosis, autoreactive CD4(+) T-helper cells accumulate in the atherosclerotic plaque. Apolipoprotein B(100) (apoB), the core protein of low-density lipoprotein, is an autoantigen that drives the generation of pathogenic T-helper type 1 (T...

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Detalles Bibliográficos
Autores principales: Wolf, Dennis, Gerhardt, Teresa, Winkels, Holger, Michel, Nathaly Anto, Pramod, Akula Bala, Ghosheh, Yanal, Brunel, Simon, Buscher, Konrad, Miller, Jacqueline, McArdle, Sara, Baas, Livia, Kobiyama, Kouji, Vassallo, Melanie, Ehinger, Erik, Dileepan, Thamotharampillai, Ali, Amal, Schell, Maximilian, Mikulski, Zbigniew, Sidler, Daniel, Kimura, Takayuki, Sheng, Xia, Horstmann, Hauke, Hansen, Sophie, Mitre, Lucia Sol, Stachon, Peter, Hilgendorf, Ingo, Gaddis, Dalia E., Hedrick, Catherine, Benedict, Chris A., Peters, Bjoern, Zirlik, Andreas, Sette, Alessandro, Ley, Klaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2020
Materias:
Original Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7515473/
https://www.ncbi.nlm.nih.gov/pubmed/32703007
http://dx.doi.org/10.1161/CIRCULATIONAHA.119.042863

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