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Cholesterol Alters the Orientation and Activity of the Influenza Virus M2 Amphipathic Helix in the Membrane

[Image: see text] The influenza virus M2 amphipathic helix (M2AH) alters membrane curvature in a cholesterol-dependent manner, mediating viral membrane scission during influenza virus budding. Here, we have investigated the biophysical effects of cholesterol on the ability of an M2AH peptide to mani...

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Detalles Bibliográficos
Autores principales:	Martyna, Agnieszka, Bahsoun, Basma, Madsen, Jesper J., Jackson, Frederic St. J. S., Badham, Matthew D., Voth, Gregory A., Rossman, Jeremy S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2020
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7515559/ https://www.ncbi.nlm.nih.gov/pubmed/32644803 http://dx.doi.org/10.1021/acs.jpcb.0c03331

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