Gap junctions amplify TRPV4 activation-initiated cell injury via modification of intracellular Ca(2+) and Ca(2+)-dependent regulation of TXNIP

The elevated intracellular Ca(2+) and oxidative stress are well-reported mechanisms behind renal tubular epithelial injury initiated by various insults. Given that TRPV4 and connexin43 (Cx43) channels are activated by a wide range of stimuli and regulate both intracellular Ca(2+) and redox status, w...

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Detalles Bibliográficos
Autores principales: Zhang, Xiling, Mao, Zhimin, Huang, Yanru, Zhang, Zhen, Yao, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7515575/
https://www.ncbi.nlm.nih.gov/pubmed/32752916
http://dx.doi.org/10.1080/19336950.2020.1803552

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7515575/
https://www.ncbi.nlm.nih.gov/pubmed/32752916
http://dx.doi.org/10.1080/19336950.2020.1803552

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