Cargando…

Gap junctions amplify TRPV4 activation-initiated cell injury via modification of intracellular Ca(2+) and Ca(2+)-dependent regulation of TXNIP

The elevated intracellular Ca(2+) and oxidative stress are well-reported mechanisms behind renal tubular epithelial injury initiated by various insults. Given that TRPV4 and connexin43 (Cx43) channels are activated by a wide range of stimuli and regulate both intracellular Ca(2+) and redox status, w...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Xiling, Mao, Zhimin, Huang, Yanru, Zhang, Zhen, Yao, Jian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2020
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7515575/ https://www.ncbi.nlm.nih.gov/pubmed/32752916 http://dx.doi.org/10.1080/19336950.2020.1803552

Ejemplares similares

Amplified intracellular Ca(2+) for synergistic anti-tumor therapy of microwave ablation and chemotherapy
por: Dou, Jian-ping, et al.
Publicado: (2019)

An electrostatic mechanism for Ca(2+)-mediated regulation of gap junction channels
por: Bennett, Brad C., et al.
Publicado: (2016)

TRPV4 disrupts mitochondrial transport and causes axonal degeneration via a CaMKII-dependent elevation of intracellular Ca(2+)
por: Woolums, Brian M., et al.
Publicado: (2020)

The Effect of Gap Junctional Coupling on the Spatiotemporal Patterns of Ca(2+) Signals and the Harmonization of Ca(2+)-Related Cellular Responses
por: Dougoud, Michaël, et al.
Publicado: (2016)

TRPV1 variants impair intracellular Ca(2+) signaling and may confer susceptibility to malignant hyperthermia
por: Vanden Abeele, Fabien, et al.
Publicado: (2018)

Inhibition of intracellular proton-sensitive Ca(2+)-permeable TRPV3 channels protects against ischemic brain injury
por: Chen, Xiaoling, et al.
Publicado: (2022)

The oscillation of intracellular Ca(2+) influx associated with the circadian expression of Piezo1 and TRPV4 in the bladder urothelium
por: Ihara, Tatsuya, et al.
Publicado: (2018)

Improved gliotransmission by increasing intracellular Ca(2+) via TRPV1 on multi-walled carbon nanotube platforms
por: Lee, Won-Seok, et al.
Publicado: (2022)

Ca(2+)/Calmodulin Modulates TRPV1 Activation by Capsaicin
por: Rosenbaum, Tamara, et al.
Publicado: (2004)

Acute Detubulation of Ventricular Myocytes Amplifies the Inhibitory Effect of Cholinergic Agonist on Intracellular Ca(2+) Transients
por: Belevych, Andriy E., et al.
Publicado: (2021)

Ca(2+)-Dependent and -Independent Calmodulin Binding to the Cytoplasmic Loop of Gap Junction Connexins
por: Tran, Oanh, et al.
Publicado: (2023)

The effects of mitochondrial Ca(2+) transport on intracellular Ca(2+) waves in cardiomyocytes
por: Zhao, Zhenghang, et al.
Publicado: (2012)

Presenilin-2 dampens intracellular Ca(2+) stores by increasing Ca(2+) leakage and reducing Ca(2+) uptake
por: Brunello, Lucia, et al.
Publicado: (2009)

By Regulating Mitochondrial Ca(2+)-Uptake UCP2 Modulates Intracellular Ca(2+)
por: Motloch, Lukas Jaroslaw, et al.
Publicado: (2016)

Role of intracellular Ca2+ in stimulation-induced increases in transmitter release at the frog neuromuscular junction
Publicado: (1994)

Intracellular Ca(2+) release decelerates mitochondrial cristae dynamics within the junctions to the endoplasmic reticulum
por: Gottschalk, Benjamin, et al.
Publicado: (2018)

Ca(2+) Signaling by TRPV4 Channels in Respiratory Function and Disease
por: Rajan, Suhasini, et al.
Publicado: (2021)

Influence of gap junctions upon Ca(2+) propagation from stimulated keratinocytes to DRG neurons
por: Seto, Chiaki, et al.
Publicado: (2022)

Modulation of the Voltage Sensor of L-type Ca(2+) Channels by Intracellular Ca(2+)
por: Isaev, Dmytro, et al.
Publicado: (2004)

Interplay Between Intracellular Ca(2+) Oscillations and Ca(2+)-stimulated Mitochondrial Metabolism
por: Wacquier, Benjamin, et al.
Publicado: (2016)

Comparative Ca(2+) channel contributions to intracellular Ca(2+) levels in the circadian clock
por: Plante, Amber E., et al.
Publicado: (2021)

Hypertrophic cardiomyopathy mutations increase myofilament Ca(2+) buffering, alter intracellular Ca(2+) handling, and stimulate Ca(2+)-dependent signaling
por: Robinson, Paul, et al.
Publicado: (2018)

TRPV4 Complexes With the Na(+)/Ca(2+) Exchanger and IP(3) Receptor 1 to Regulate Local Intracellular Calcium and Tracheal Tension in Mice
por: Zhang, Jie, et al.
Publicado: (2019)

Mitochondrial Participation in the Intracellular Ca(2+) Network
por: Babcock, Donner F., et al.
Publicado: (1997)

Intracellular Ca(2+)-Mediated AE2 Is Involved in the Vectorial Movement of HaCaT Keratinocyte
por: Hwang, Soyoung, et al.
Publicado: (2020)

Signaling between intracellular Ca2+ stores and depletion-activated Ca2+ channels generates [Ca2+]i oscillations in T lymphocytes
Publicado: (1994)

Pannexin 3 functions as an ER Ca(2+) channel, hemichannel, and gap junction to promote osteoblast differentiation
por: Ishikawa, Masaki, et al.
Publicado: (2011)

Divalent Heavy Metal Cations Block the TRPV1 Ca(2+) Channel
por: Pecze, László, et al.
Publicado: (2012)

Developmental Axon Degeneration Requires TRPV1-Dependent Ca(2+) Influx
por: Johnstone, Aaron D., et al.
Publicado: (2019)

Beyond Ca(2+) signalling: the role of TRPV3 in the transport of NH(4)(+)
por: Liebe, Hendrik, et al.
Publicado: (2021)

Modulation of Murine Olivary Connexin 36 Gap Junctions by PKA and CaMKII
por: Bazzigaluppi, Paolo, et al.
Publicado: (2017)

STIM2 regulates both intracellular Ca(2+) distribution and Ca(2+) movement in skeletal myotubes
por: Oh, Mi Ri, et al.
Publicado: (2017)

Endothelial TRPV4 channels modulate vascular tone by Ca(2+)‐induced Ca(2+) release at inositol 1,4,5‐trisphosphate receptors
por: Heathcote, Helen R., et al.
Publicado: (2019)

Smooth muscle gap-junctions allow propagation of intercellular Ca(2+) waves and vasoconstriction due to Ca(2+) based action potentials in rat mesenteric resistance arteries
por: Borysova, Lyudmyla, et al.
Publicado: (2018)

Effects of butyrate(−) on ruminal Ca(2+) transport: evidence for the involvement of apically expressed TRPV3 and TRPV4 channels
por: Liebe, Franziska, et al.
Publicado: (2022)

Ca(2+) Cycling in Heart Cells from Ground Squirrels: Adaptive Strategies for Intracellular Ca(2+) Homeostasis
por: Li, Xiao-Chen, et al.
Publicado: (2011)

Muscle aging is associated with compromised Ca(2+) spark signaling and segregated intracellular Ca(2+) release
por: Weisleder, Noah, et al.
Publicado: (2006)

The Role of the Na(+)/Ca(2+) Exchanger in Aberrant Intracellular Ca(2+) in Cardiomyocytes of Chagas-Infected Rodents
por: Lopez, Jose R., et al.
Publicado: (2022)

TRPV1 alleviates osteoarthritis by inhibiting M1 macrophage polarization via Ca(2+)/CaMKII/Nrf2 signaling pathway
por: Lv, Zhongyang, et al.
Publicado: (2021)

Powering the plasma membrane Ca(2+)-ROS self-amplifying loop
por: Pottosin, Igor, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_naobvpfvv2ltg8e7kma1154d2l