Molecular Diagnosis of Coronavirus Disease 2019

OBJECTIVES: To review molecular diagnostics for coronavirus disease 2019. The world is in the midst of a coronavirus disease 2019 pandemic. Containing the spread of the severe acute respiratory distress coronavirus is critical. Instrumental to the future success is the ability to reliably and reprod...

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Detalles Bibliográficos
Autores principales: dos Santos, Claudia C., Zehnbauer, Barbara A., Trahtemberg, Uriel, Marshall, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2020
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7515613/
https://www.ncbi.nlm.nih.gov/pubmed/33063040
http://dx.doi.org/10.1097/CCE.0000000000000184
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author dos Santos, Claudia C.
Zehnbauer, Barbara A.
Trahtemberg, Uriel
Marshall, John
author_facet dos Santos, Claudia C.
Zehnbauer, Barbara A.
Trahtemberg, Uriel
Marshall, John
author_sort dos Santos, Claudia C.
collection PubMed
description OBJECTIVES: To review molecular diagnostics for coronavirus disease 2019. The world is in the midst of a coronavirus disease 2019 pandemic. Containing the spread of the severe acute respiratory distress coronavirus is critical. Instrumental to the future success is the ability to reliably and reproducibly detect this inciting pathogen to inform public health containment policies and treatment decisions. DATA SOURCES: Molecular diagnostics focusing on molecular detection methodologies for detection of the virus and the presence of the disease. STUDY SELECTION: Narrative review. DATA EXTRACTION: Literature, PubMed, Scopus, and official government documents. DATA SYNTHESIS: Diagnosing severe acute respiratory syndrome coronavirus is done through real-time reverse transcriptase-polymerase chain reaction tests, cell culture, and serology. For patients, diagnostics are an integral part of a full medical history, physical examinations, blood tests, and diagnostic imaging. CONCLUSIONS: Here, we review current approaches to the molecular diagnosis of coronavirus disease 2019.
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spelling pubmed-75156132020-10-14 Molecular Diagnosis of Coronavirus Disease 2019 dos Santos, Claudia C. Zehnbauer, Barbara A. Trahtemberg, Uriel Marshall, John Crit Care Explor Review Article OBJECTIVES: To review molecular diagnostics for coronavirus disease 2019. The world is in the midst of a coronavirus disease 2019 pandemic. Containing the spread of the severe acute respiratory distress coronavirus is critical. Instrumental to the future success is the ability to reliably and reproducibly detect this inciting pathogen to inform public health containment policies and treatment decisions. DATA SOURCES: Molecular diagnostics focusing on molecular detection methodologies for detection of the virus and the presence of the disease. STUDY SELECTION: Narrative review. DATA EXTRACTION: Literature, PubMed, Scopus, and official government documents. DATA SYNTHESIS: Diagnosing severe acute respiratory syndrome coronavirus is done through real-time reverse transcriptase-polymerase chain reaction tests, cell culture, and serology. For patients, diagnostics are an integral part of a full medical history, physical examinations, blood tests, and diagnostic imaging. CONCLUSIONS: Here, we review current approaches to the molecular diagnosis of coronavirus disease 2019. Lippincott Williams & Wilkins 2020-09-17 /pmc/articles/PMC7515613/ /pubmed/33063040 http://dx.doi.org/10.1097/CCE.0000000000000184 Text en Copyright © 2020 The Authors. Published by Wolters Kluwer Health, Inc. on behalf of the Society of Critical Care Medicine. This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND) (http://creativecommons.org/licenses/by-nc-nd/4.0/) , where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal. This article is made available via the PMC Open Access Subset for unrestricted re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the COVID-19 pandemic or until permissions are revoked in writing. Upon expiration of these permissions, PMC is granted a perpetual license to make this article available via PMC and Europe PMC, consistent with existing copyright protections.
spellingShingle Review Article
dos Santos, Claudia C.
Zehnbauer, Barbara A.
Trahtemberg, Uriel
Marshall, John
Molecular Diagnosis of Coronavirus Disease 2019
title Molecular Diagnosis of Coronavirus Disease 2019
title_full Molecular Diagnosis of Coronavirus Disease 2019
title_fullStr Molecular Diagnosis of Coronavirus Disease 2019
title_full_unstemmed Molecular Diagnosis of Coronavirus Disease 2019
title_short Molecular Diagnosis of Coronavirus Disease 2019
title_sort molecular diagnosis of coronavirus disease 2019
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7515613/
https://www.ncbi.nlm.nih.gov/pubmed/33063040
http://dx.doi.org/10.1097/CCE.0000000000000184
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