Cargando…

Donor HLA−DR Drives the Development of De Novo Autoimmunity Following Lung and Heart Transplantation

Individuals harbor preexisting HLA−DR/DQ−restricted responses to collagen type V (ColV) mediated by Th17 cells under Treg control, both specific to peptides that bind to inherited HLA class II antigens. Yet after transplant, the donor−DR type somehow influences graft outcome. We hypothesized that, l...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jankowska−Gan, Ewa, Agashe, Vrushali V., Lema, Diego A., Zhou, Ying, Gonzalez Bosc, Laura, Sullivan, Jeremy A., Greenspan, Daniel S., Burlingham, William J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2020
Materias:	Basic Science
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7515617/ https://www.ncbi.nlm.nih.gov/pubmed/33062840 http://dx.doi.org/10.1097/TXD.0000000000001062

Ejemplares similares

Epitope Analysis of the Collagen Type V-Specific T Cell Response in Lung Transplantation Reveals an HLA-DRB1*15 Bias in Both Recipient and Donor
por: Keller, Melissa R., et al.
Publicado: (2013)

Extracellular Vesicle–associated GARP/TGFβ:LAP Mediates “Infectious” Allo-tolerance
por: Burlingham, William J., et al.
Publicado: (2023)

Identification of PD1-mediated regulation of antitumor antigen response in patients with NSCLC using the trans vivo DTH assay
por: Lema, Diego A, et al.
Publicado: (2020)

Patterns of Immune Regulation in Rhesus Macaque and Human Families
por: Burlingham, William J., et al.
Publicado: (2015)

Kinetics of Alloantigen-Specific Regulatory CD4 T Cell Development and Tissue Distribution After Donor-Specific Transfusion and Costimulatory Blockade
por: Tomita, Yusuke, et al.
Publicado: (2016)

Cross‐decoration of dendritic cells by non‐inherited maternal antigen‐containing extracellular vesicles: Potential mechanism for PD‐L1‐based tolerance in cord blood and organ transplantation
por: Lema, Diego A., et al.
Publicado: (2022)

Immunoregulatory T cells, LFA-3 and HLA-DR in autoimmune thyroid diseases
por: Nada, Aml Mohamed, et al.
Publicado: (2014)

A humanized HLA-DR4 mouse model for autoimmune myocarditis
por: Şelli, M. Emrah, et al.
Publicado: (2017)

HLA-A AND HLA-B ALLELES ASSOCIATED IN PSORIASIS PATIENTS FROM MUMBAI, WESTERN INDIA
por: Umapathy, Shankarkumar, et al.
Publicado: (2011)

The natural history of de novo donor-specific HLA antibodies after kidney transplantation
por: López del Moral, Covadonga, et al.
Publicado: (2022)

Distinct antibody profiles in HLA-B(∗)57(+), HLA-B(∗)57(−) HIV controllers and chronic progressors
por: Klingler, Jéromine, et al.
Publicado: (2022)

HLA-DR, HLA-DQB1 and PTPN22 gene polymorphism: association with age at onset for autoimmune diabetes
por: Okruszko, Anna, et al.
Publicado: (2012)

Evaluation of the role of HLA-DR antigens in Japanese type 1 autoimmune hepatitis
por: Furumoto, Yohei, et al.
Publicado: (2015)

CTLA-4 gene polymorphisms and their influence on predisposition to autoimmune thyroid diseases (Graves’ disease and Hashimoto's thyroiditis)
por: Pastuszak-Lewandoska, Dorota, et al.
Publicado: (2012)

Interleukin 10 Induces the Expression of Membrane-Bound HLA- G and the Production of Soluble HLA-G on HeLa CCL-2 Cells
por: Hasanah, Nurul, et al.
Publicado: (2019)

Anti-phosphatidylserine/prothrombin antibodies and thrombosis associate positively with HLA-DRB1*13 and negatively with HLA-DRB1*03 in SLE
por: Elbagir, Sahwa, et al.
Publicado: (2022)

HLA, gut microbiome and hepatic autoimmunity
por: Terziroli Beretta-Piccoli, Benedetta, et al.
Publicado: (2022)

IMPACT OF HLA-G IN THE OUTCOME OF VITILIGO IN TUNISIAN PATIENTS
por: Jalel, Akrem, et al.
Publicado: (2010)

HLA-DM Interactions with Intermediates in HLA-DR Maturation and a Role for HLA-DM in Stabilizing Empty HLA-DR Molecules
por: Denzin, Lisa K., et al.
Publicado: (1996)

Association of HLA-DR1, HLA-DR13, and HLA-DR16 Polymorphisms with Systemic Lupus Erythematosus: A Meta-Analysis
por: Wang, Tingrui, et al.
Publicado: (2022)

HLA-DR, and not PLA2R, is expressed on the podocytes in kidney allografts in de novo membranous nephropathy
por: Wen, Jiqiu, et al.
Publicado: (2016)

Characteristics and Clinical Significance of De Novo Donor-Specific Anti-HLA Antibodies after Kidney Transplantation
por: Jung, Hee-Yeon, et al.
Publicado: (2018)

Matching for HLA-DR excluding diabetogenic HLA-DR3 and HLA-DR4 predicts insulin independence after pancreatic islet transplantation
por: Ballou, Cassandra, et al.
Publicado: (2023)

Increased HLA-DR expression and cortical demyelination in MS links with HLA-DR15
por: Enz, Lukas Simon, et al.
Publicado: (2019)

HLA-DR Mismatch and Black Race Are Associated With Recurrent Autoimmune Hepatitis After Liver Transplantation
por: McCabe, Marshall, et al.
Publicado: (2021)

Association of HLA-DR3 and HLA-DR15 Polymorphisms with Risk of Systemic Lupus Erythematosus
por: Xue, Ke, et al.
Publicado: (2018)

Many de novo donor‐specific antibodies recognize β(2)‐microglobulin‐free, but not intact HLA heterodimers
por: Michel, K., et al.
Publicado: (2016)

Importance and What to Watch Out for De Novo Donor Specific Anti-HLA Antibodies after Kidney Transplantation
por: Yang, Chul Woo
Publicado: (2018)

HLA Ligand Atlas: a benign reference of HLA-presented peptides to improve T-cell-based cancer immunotherapy
por: Marcu, Ana, et al.
Publicado: (2021)

Differential role of HLA-A and HLA-B, C expression levels as prognostic markers in colon and rectal cancer
por: Michelakos, Theodoros, et al.
Publicado: (2022)

Minor H Antigen HA-1–specific Regulator and Effector CD8(+) T Cells, and HA-1 Microchimerism, in Allograft Tolerance
por: Cai, Junchao, et al.
Publicado: (2004)

Identification of neoepitope reactive T-cell receptors guided by HLA-A*03:01 and HLA-A*11:01 immunopeptidomics
por: Ade, Catherine M, et al.
Publicado: (2023)

The arthritis-associated HLA-B*27:05 allele forms more cell surface B27 dimer and free heavy chain ligands for KIR3DL2 than HLA-B*27:09
por: Cauli, Alberto, et al.
Publicado: (2013)

HLA-DRB1 polymorphism determines susceptibility to autoimmune thyroiditis in transgenic mice: definitive association with HLA- DRB1*0301 (DR3) gene
Publicado: (1996)

Do Non-HLA Genes Influence Development of Persistent Islet Autoimmunity and Type 1 Diabetes in Children With High-Risk HLA-DR,DQ Genotypes?
por: Steck, Andrea K., et al.
Publicado: (2009)

Effects of Non-HLA Gene Polymorphisms on Development of Islet Autoimmunity and Type 1 Diabetes in a Population With High-Risk HLA-DR,DQ Genotypes
por: Steck, Andrea K., et al.
Publicado: (2012)

HY Immune Tolerance Is Common in Women without Male Offspring
por: Dierselhuis, Miranda P., et al.
Publicado: (2014)

The Influence of Immunosuppressive Agents on the Risk of De Novo Donor-Specific HLA Antibody Production in Solid Organ Transplant Recipients
por: O'Leary, Jacqueline G., et al.
Publicado: (2016)

T cells sensitized to synthetic HLA-DR3 peptide give evidence of continuous presentation of denatured HLA-DR3 molecules by HLA-DP
Publicado: (1989)

Novel HLA Class I Alleles Outside the Extended DR3 Haplotype Are Protective against Autoimmune Hepatitis
por: Lammert, Craig, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_tv5phvn7rgmfbg7kvv1rfcnrvk