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Optogenetic activation of heterotrimeric G-proteins by LOV2GIVe, a rationally engineered modular protein

Heterotrimeric G-proteins are signal transducers involved in mediating the action of many natural extracellular stimuli and many therapeutic agents. Non-invasive approaches to manipulate the activity of G-proteins with high precision are crucial to understand their regulation in space and time. Here...

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Detalles Bibliográficos
Autores principales:	Garcia-Marcos, Mikel, Parag-Sharma, Kshitij, Marivin, Arthur, Maziarz, Marcin, Luebbers, Alex, Nguyen, Lien T
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2020
Materias:	Biochemistry and Chemical Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7515630/ https://www.ncbi.nlm.nih.gov/pubmed/32936073 http://dx.doi.org/10.7554/eLife.60155

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