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Risk Factors for Predicting Hypoxia in Adult Patients Undergoing Bronchoscopy under Sedation
BACKGROUND: Flexible bronchoscopy is one of the essential procedures for the diagnosis and treatment of pulmonary diseases. The purpose of this study was to identify the risk factors associated with the occurrence of hypoxia in adults undergoing flexible bronchoscopy under sedation. METHODS: We retr...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Academy of Tuberculosis and Respiratory Diseases
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7515671/ https://www.ncbi.nlm.nih.gov/pubmed/32640767 http://dx.doi.org/10.4046/trd.2020.0002 |
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author | Choi, Ji Soo Lee, Eun Hye Lee, Sang Hoon Leem, Ah Young Chung, Kyung Soo Kim, Song Yee Jung, Ji Ye Kang, Young Ae Park, Moo Suk Chang, Joon Kim, Young Sam |
author_facet | Choi, Ji Soo Lee, Eun Hye Lee, Sang Hoon Leem, Ah Young Chung, Kyung Soo Kim, Song Yee Jung, Ji Ye Kang, Young Ae Park, Moo Suk Chang, Joon Kim, Young Sam |
author_sort | Choi, Ji Soo |
collection | PubMed |
description | BACKGROUND: Flexible bronchoscopy is one of the essential procedures for the diagnosis and treatment of pulmonary diseases. The purpose of this study was to identify the risk factors associated with the occurrence of hypoxia in adults undergoing flexible bronchoscopy under sedation. METHODS: We retrospectively analyzed 2,520 patients who underwent flexible bronchoscopy under sedation at our tertiary care university hospital in South Korea January 1, 2013–December 31, 2014. Hypoxia was defined as more than 5%-point reduction in the baseline percutaneous oxygen saturation (SpO(2)) or SpO(2) <90% for >1 minute during the procedure. RESULTS: The mean age was 64.7±13.5, and 565 patients developed hypoxia during the procedure. The mean sedation duration and midazolam dose for sedation were 31.1 minutes and 3.9 mg, respectively. The bivariate analysis showed that older age, a low forced expiratory volume in one second (FEV(1)), use of endobronchial ultrasound, the duration of sedation, and the midazolam dose were associated with the occurrence of hypoxia during the procedure, while the multivariate analysis found that age >60 (odds ratio [OR], 1.32), a low FEV(1) (OR, 0.99), and a longer duration of sedation (>40 minutes; OR, 1.33) were significant risk factors. CONCLUSION: The findings suggest that patients older than age 60 and those with a low FEV(1) tend to develop hypoxia during the bronchoscopy under sedation. Also, longer duration of sedation (>40 minutes) was a significant risk factor for hypoxia. |
format | Online Article Text |
id | pubmed-7515671 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | The Korean Academy of Tuberculosis and Respiratory Diseases |
record_format | MEDLINE/PubMed |
spelling | pubmed-75156712020-10-03 Risk Factors for Predicting Hypoxia in Adult Patients Undergoing Bronchoscopy under Sedation Choi, Ji Soo Lee, Eun Hye Lee, Sang Hoon Leem, Ah Young Chung, Kyung Soo Kim, Song Yee Jung, Ji Ye Kang, Young Ae Park, Moo Suk Chang, Joon Kim, Young Sam Tuberc Respir Dis (Seoul) Original Article BACKGROUND: Flexible bronchoscopy is one of the essential procedures for the diagnosis and treatment of pulmonary diseases. The purpose of this study was to identify the risk factors associated with the occurrence of hypoxia in adults undergoing flexible bronchoscopy under sedation. METHODS: We retrospectively analyzed 2,520 patients who underwent flexible bronchoscopy under sedation at our tertiary care university hospital in South Korea January 1, 2013–December 31, 2014. Hypoxia was defined as more than 5%-point reduction in the baseline percutaneous oxygen saturation (SpO(2)) or SpO(2) <90% for >1 minute during the procedure. RESULTS: The mean age was 64.7±13.5, and 565 patients developed hypoxia during the procedure. The mean sedation duration and midazolam dose for sedation were 31.1 minutes and 3.9 mg, respectively. The bivariate analysis showed that older age, a low forced expiratory volume in one second (FEV(1)), use of endobronchial ultrasound, the duration of sedation, and the midazolam dose were associated with the occurrence of hypoxia during the procedure, while the multivariate analysis found that age >60 (odds ratio [OR], 1.32), a low FEV(1) (OR, 0.99), and a longer duration of sedation (>40 minutes; OR, 1.33) were significant risk factors. CONCLUSION: The findings suggest that patients older than age 60 and those with a low FEV(1) tend to develop hypoxia during the bronchoscopy under sedation. Also, longer duration of sedation (>40 minutes) was a significant risk factor for hypoxia. The Korean Academy of Tuberculosis and Respiratory Diseases 2020-10 2020-07-09 /pmc/articles/PMC7515671/ /pubmed/32640767 http://dx.doi.org/10.4046/trd.2020.0002 Text en Copyright © 2020 The Korean Academy of Tuberculosis and Respiratory Diseases It is identical to the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/). |
spellingShingle | Original Article Choi, Ji Soo Lee, Eun Hye Lee, Sang Hoon Leem, Ah Young Chung, Kyung Soo Kim, Song Yee Jung, Ji Ye Kang, Young Ae Park, Moo Suk Chang, Joon Kim, Young Sam Risk Factors for Predicting Hypoxia in Adult Patients Undergoing Bronchoscopy under Sedation |
title | Risk Factors for Predicting Hypoxia in Adult Patients Undergoing Bronchoscopy under Sedation |
title_full | Risk Factors for Predicting Hypoxia in Adult Patients Undergoing Bronchoscopy under Sedation |
title_fullStr | Risk Factors for Predicting Hypoxia in Adult Patients Undergoing Bronchoscopy under Sedation |
title_full_unstemmed | Risk Factors for Predicting Hypoxia in Adult Patients Undergoing Bronchoscopy under Sedation |
title_short | Risk Factors for Predicting Hypoxia in Adult Patients Undergoing Bronchoscopy under Sedation |
title_sort | risk factors for predicting hypoxia in adult patients undergoing bronchoscopy under sedation |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7515671/ https://www.ncbi.nlm.nih.gov/pubmed/32640767 http://dx.doi.org/10.4046/trd.2020.0002 |
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