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Structural and mechanistic insights into the CRISPR inhibition of AcrIF7

The CRISPR–Cas system provides adaptive immunity for bacteria and archaea to combat invading phages and plasmids. Phages evolved anti-CRISPR (Acr) proteins to neutralize the host CRISPR–Cas immune system as a counter-defense mechanism. AcrIF7 in Pseudomonas aeruginosa prophages strongly inhibits the...

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Detalles Bibliográficos
Autores principales:	Kim, Iktae, Koo, Jasung, An, So Young, Hong, Suji, Ka, Donghyun, Kim, Eun-Hee, Bae, Euiyoung, Suh, Jeong-Yong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2020
Materias:	Structural Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7515697/ https://www.ncbi.nlm.nih.gov/pubmed/32810226 http://dx.doi.org/10.1093/nar/gkaa690

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