Robust partitioning of microRNA targets from downstream regulatory changes

The biological impact of microRNAs (miRNAs) is determined by their targets, and robustly identifying direct miRNA targets remains challenging. Existing methods suffer from high false-positive rates and are unable to effectively differentiate direct miRNA targets from downstream regulatory changes. H...

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Detalles Bibliográficos
Autores principales: Patel, Ravi K, West, Jessica D, Jiang, Ya, Fogarty, Elizabeth A, Grimson, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7515711/
https://www.ncbi.nlm.nih.gov/pubmed/32821933
http://dx.doi.org/10.1093/nar/gkaa687

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7515711/
https://www.ncbi.nlm.nih.gov/pubmed/32821933
http://dx.doi.org/10.1093/nar/gkaa687

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